Kanamycin sulfate is a water soluble broad spectrum antibiotic obtained from soil bacterium Streptomyces kanamyceticus. It is an aminoglycoside antibiotic effective against Gram-negative and Grampositive bacteria and mycoplasma. It binds to the 70S ribosomal subunit, inhibits translocation, and elicits miscoding. Cross-resistance occurs between kanamycin and neomycin, framycetin, and paromomycin, and partial cross-resistance has been reported between kanamycin and streptomycin. Aminoglycoside-modifying enzymes (acetyltransferase, phosphotransferase, nucleotidyltransferase) alter the antibiotic, preventing its interaction with ribosomes.
A009 is sterile filtered solution formulated to contain 50mg/ml Kanamycin
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