DEAE μSphere is a weak anion exchanger based on the well established μSphere ion exchange platform, extensively used for preparative protein separations in both research and industrial applications.
Well-proven weak anion exchanger developed for industrial downstream processes
Used extensively for capture and intermediate purification of a wide range of approved biopharmaceuticals
The industry standard for ion exchange chromatography during recent decades
High chemical stability allows for well proven CIP and sanitization protocols
The hydrophilic nature of the base matrix ensures low levels of non-specific binding leading to low levels of host cell-derived impurities in the elution pool.
DEAE μSphere is part of the μSphere ion exchange platform, which has been the industrial standard for ion exchange chromatography during recent decades. It is composed of cross-linked, polymer particles, with diethylaminoethyl (DEAE) weak anion exchange groups. DEAE μSphere has high chemical stability, allowing well proven cleaning-in-place (CIP) and sanitization protocols. Scale-up with DEAE μSphere is straight forward and the resin is available in a range of pre-packed process development tools.
As member of the BioProcess resins range, DEAE μSphere meets industrial demands with security of supply and comprehensive technical and regulatory support.
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