Heparin mSphere is a well established BioProcess affinity resin designed for capture or intermediate purification steps. This resin is extensively used for industrial purification of several marketed plasma proteins.
Industrial purification of antithrombin III, coagulation factors and other plasma proteins
Coupling chemistry gives chemically-stable ligand attachment. Stability of resin solely dictated by heparin ligand.
BioProcess resin supported for industrial applications and well-established in approved processes
Heparin mSphere is a member of the range of affinity chromatography resins for capture and intermediate purification.
Heparin mSphere is composed of cross-linked 6% agarose beads modified sodium heparin. Immobilization is performed using chemically stable and oriented coupling giving high binding capacity. The chemical stability of the resin is solely dictated by the heparin ligand.
This resin allows for fast and reliable separations of biomolecules with an affinity for heparin, including antithrombin III, coagulation factors and other plasma proteins. Additional applications include DNA binding proteins, lipoproteins, protein synthesis factors, enzymes that act on nucleic acids, and steroid receptors.
Heparin mSphere is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development.
As member of the BioProcess resin range, Heparin mSphere meets industrial demands with security of supply and comprehensive technical and regulatory support
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